String Bio achieves GRAS Status for Microbial Protein Ingredient, PRO-DG™ used in feed

The GRAS status, governed by the US Food and Drug Administration (FDA), sets a high standard for ingredients to be approved for use in both feed and food.

Bangalore based String Bio, a pioneering biotech company announced the self-determined Generally Recognized as Safe (GRAS) status of its innovative microbial protein, PRO-DG™, for use in crustacean feed in the U.S. This landmark achievement was affirmed by an independent panel of experts who rigorously evaluated the body of published data supporting the safety of PRO-DG™ for its intended use.

The GRAS status, governed by the US Food and Drug Administration (FDA), sets a high standard for ingredients to be approved for use in both feed and food. String Bio’s PRO-DG™ stands out as it contains approximately 70 per cent protein derived from methanotrophic bacteria, manufactured through the company’s patented String Integrated Methane Platform (SIMP®). This advanced platform ensures an ideal amino acid profile, resulting in high digestibility and performance, as validated in various aqua trials. Notably, the protein’s tolerability by shrimp was evidenced through peer-reviewed publications (Felix et al., 2023; Nederlof et al., 2023). 

With the global population projected to reach 10 billion by 2050, the demand for sustainable and traceable protein sources is critical. The total aquaculture production is expected to expand to 109 million tonnes by 2030. PRO-DG™ addresses this “protein challenge” by offering a sustainable feed ingredient, essential for the growing aquaculture market while protecting marine ecosystems and resources.

Achieving GRAS status distinguishes String Bio from other players in the alternative protein industry. This milestone, which took over two years of comprehensive scientific documentation and safety studies, validates the company’s commitment to science- based innovation.

Speaking on the announcement, Dr Ezhil Subbian, CEO, String Bio said, “The FDA-regulated GRAS status will enable the commercialization of PRO-DG™ in the United States, opening new markets and opportunities for growth. Many countries look to GRAS status as a strong indication that a feed ingredient has been rigorously tested to meet the highest standard. GRAS status of PRO-DGTM is an important milestone in String’s journey and will boost String Bio’s market presence in the feed sector.”

The GRAS status, governed by the US