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Thursday / November 21. 2024
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The GRAS status, governed by the US Food and Drug Administration (FDA), sets a high standard for ingredients to be approved for use in both feed and food.

Bangalore based String Bio, a pioneering biotech company announced the self-determined Generally Recognized as Safe (GRAS) status of its innovative microbial protein, PRO-DG™, for use in crustacean feed in the U.S. This landmark achievement was affirmed by an independent panel of experts who rigorously evaluated the body of published data supporting the safety of PRO-DG™ for its intended use.

The GRAS status, governed by the US Food and Drug Administration (FDA), sets a high standard for ingredients to be approved for use in both feed and food. String Bio’s PRO-DG™ stands out as it contains approximately 70 per cent protein derived from methanotrophic bacteria, manufactured through the company’s patented String Integrated Methane Platform (SIMP®). This advanced platform ensures an ideal amino acid profile, resulting in high digestibility and performance, as validated in various aqua trials. Notably, the protein’s tolerability by shrimp was evidenced through peer-reviewed publications (Felix et al., 2023; Nederlof et al., 2023). 

With the global population projected to reach 10 billion by 2050, the demand for sustainable and traceable protein sources is critical. The total aquaculture production is expected to expand to 109 million tonnes by 2030. PRO-DG™ addresses this “protein challenge” by offering a sustainable feed ingredient, essential for the growing aquaculture market while protecting marine ecosystems and resources.

Achieving GRAS status distinguishes String Bio from other players in the alternative protein industry. This milestone, which took over two years of comprehensive scientific documentation and safety studies, validates the company’s commitment to science- based innovation.

Speaking on the announcement, Dr Ezhil Subbian, CEO, String Bio said, “The FDA-regulated GRAS status will enable the commercialization of PRO-DG™ in the United States, opening new markets and opportunities for growth. Many countries look to GRAS status as a strong indication that a feed ingredient has been rigorously tested to meet the highest standard. GRAS status of PRO-DGTM is an important milestone in String’s journey and will boost String Bio’s market presence in the feed sector.”

The GRAS status, governed by the US

Bangalore-based String Bio, an innovator that is redefining sustainable manufacturing, announced today that its animal nutrition product – PRO-DG® has been successfully tested and validated in Salmon feed by BioMar, a global leader in sustainable aquaculture feeds. BioMar paid particular attention to the evaluation of this new unicellular protein, which they have been working on for some time together with String Bio, with the intention of biologically evaluating the product, calculating its value in diets, and trying to help the process of commercial acceleration of this interesting new raw material.

String is one of the world leaders in gas fermentation, scaling up economical and modular fermenters that enable the production of high-quality ingredients from greenhouse gases. PRO-DG® is an alternative protein ingredient with optimal nutritional factors, manufactured by the platform. It provides traceability, significantly optimizes the use of land and water, and provides sustainability to the feed value chain. Key performance and physiological parameters from the trials validated the use of PRO-DG as a feed ingredient in Salmon diets. In previous trials with renowned institutes, PRO-DG has been found to increase feed conversion and growth rates in shrimp, poultry and other species as well.

With the global population set to increase to almost 10 billion people by 2050 and the growing demand for fish as an ideal protein source, the market is facing a potential ‘protein challenge’. According to the report The State of World Fisheries and Aquaculture 2020, the total aquaculture production is expected to expand from 26 million tonne in 2018 to 109 million tonne in 2030. Sustainable and traceable fish feeds are thus needed to meet the growing demand while ensuring protection of marine ecosystems and ocean resources. The introduction and large-scale adoption of alternative protein ingredients, like PRO-DG, in aquaculture feed can be central to strengthening global food security and lessening pressure on wild fish stocks and the ocean ecosystem.

Commenting on the successful trial, Dr Ezhil Subbian, Co-Founder & CEO, String Bio said “String has been validating the use of PRO-DG across various species in different geographies and varying farm management practices. It’s a great milestone to have the validation studies done by Biomar, an industry leader in the Aqua nutrition sector. We look forward to taking the work ahead with them to drive commercial adoption of novel ingredients in Aquaculture.”

“At BioMar we are constantly seeking innovative raw materials that are aligned with our strategic ambitions to help develop circular & restorative ingredients. The preliminary results of the validation highlight the biological potential of PRO-DG® as a protein alternative within our current basket of raw materials to reduce carbon emissions”, said Fernando Norambuena, Global Category Manager – Novel Raw Materials, BioMar.

Bangalore-based String Bio, an innovator that is